Essential and other Functions:

50% Animal Experimentation
Managing production of experimental animals for the needs of all iBAM members. Coordinate and lead animal tissue dissections for efficient sample collection for experimental needs. Animal husbandry, mouse colony management, collect and record data collected on live animals, mouse necropsies, collection and preservation of biological samples, performs IVIS imaging, dosing mice for drug studies, communicates with RAR veterinary staff concerning animal health cases, facilitates animal transfers, monitors health of experimental animals.

25% Sample and Data Management
Sample and Data Management: Using the lab’s unique colony management database, create animal identifiers and cage cards, prepare necropsy reports and labels for biologic samples, archive samples in the tissue bank and ship biological samples to collaborators, maintain up to date records of culling and anesthesia logs.

10% Cellular and Molecular biology
Prepare tissue lysates, isolate RNA and protein, quantitate nucleic acids and protein levels, perform qRT-PCR, PCR genotyping, nucleic acid and protein electrophoresis, prepare and refresh cell culture media. Establishing and maintaining mouse embryonic fibroblasts and culture of neuronal cell lines for functional assays.

15% Supervision:
Training new lab staff and on IVIS, mouse colony management, animal husbandry and tissue collection techniques, delegates colony management responsibilities.


Qualifications
All required qualifications must be documented on application materials

Required Qualifications:

BS/BA in a biomedical discipline and 1 year of experience, or a combination of related education and work experience to equal 5 years.
Experience working with mice or similar model organisms.
Mouse colony management or similar experience in managing large, complex projects.
Strong interest in gaining an understanding of DNA damage, DNA repair and genome instability disorders.
Strong ability to work with coworkers, colleagues, and collaborators to reach goals in a timely and efficient manner.
Must have strong problem-solving skills, an ability to multitask and to work independently and as a group.
Preferred Qualifications:

Applicants should have an interest in health sciences and interest in working with laboratory animals.
About the Department
Institute on Biology of Aging and Metabolism

Our research program is focused on investigating the underlying causes of aging. We use mouse models extensively, employing both genetic and pharmacologic approaches to interrogate mechanisms of aging. Aging is investigated in vivo by measuring senescence, frailty, organ function and behavior. The candidate will join an exciting research environment in the Department of Biochemistry, Molecular Biology, and Biophysics and the Institute on the Biology of Aging and Metabolism at the University of Minnesota Twin Cities. The position offers exceptional training in animal physiology, aging, age-related disease and pre-clinical testing of drugs.